The present invention provides a nanovehicle useful for targeted and controlled delivery of a therapeutic molecule. The nanovehicle comprises complex of a nanopolymer, a therapeutic molecule and a targeting ligand of sequence Id no.l.The nanovehicle is efficient for the targeted delivery of a biotherapeutic like drug and/or siRNA along with providing technical advantages like insignificant cross-reactivity at by stander organs along with providing enhanced bioavailability and higher retention of the molecule in blood.