KLAUS, STEPHEN J.,MOLINEAUX, CHRISTOPHER J.,NEFF, THOMAS B.,GUENZLER-PUKALL, VOLKMAR,LANSETMO PAROBOK, INGRID,SEELEY, TODD W.,STEPHENSON, ROBERT C.
申请号:
CA2526496
公开号:
CA2526496C
申请日:
2004.06.04
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to methods and compounds for regulating orenhancingerythropoiesis and iron metabolism, and for treating or preventing irondeficiency and anemia ofchronic disease. Such compounds are ones that inhibit HIF prolyl hydroxylaseactivity that is astructural mimetic of 2-oxoglutarate. Examples include compounds of formula(I).(see formula I)