An ultrasound diagnostic apparatus adapted for vascular wall elastic modulus measurement comprises an ultrasound probe, an actuation controller, an image producer, a region-of-interest setter, and a storage unit. The apparatus sets a region of interest, incorporates ultrasonic wave transmission/reception for obtaining an ultrasound image including the region of interest into ultrasonic wave transmission/reception for obtaining an ultrasound image of the region of interest at a predetermined timing, and stores the obtained two ultrasound images in association with each other, which makes the region of interest easier to find in an ultrasound image for diagnosis, and allows a satisfactory follow-up.