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LIOFILIZIRANI SPOJ
专利权人:
MedSkin Solutions Dr. Suwelack AG
发明人:
Kuhlmann, Fabian,Elsinghorst, Claudia,Wagner, Uwe,Malessa, Ralf
申请号:
HRP20171270
公开号:
HRP20171270T1
申请日:
2017.08.18
申请国别(地区):
HR
年份:
2017
代理人:
摘要:
Freeze-dried molded body comprises (in wt.%): at least one active ingredient (>;= 50); at least one scaffold forming material (= 15), where proteins are excluded; and optionally at least one excipient each based on the total composition of the molded body. The solution or suspension of the components (1 wt.%) in water exhibits a pH of 7 at 20[deg] C. Independent claims are also included for: (1) producing the freeze-dried molded body comprising (a) producing an aqueous solution or a suspension containing at least one scaffold forming material, where proteins are excluded, at least one active ingredient and optionally at least one excipient, (b) optionally adjusting the pH of the aqueous solution or the suspension to a pH of less than 7, (c) pouring the mixture into a mold, (d) freezing the mixture into the mold, and (e) freeze drying the frozen mixture to form the molded body; and (2) a kit-of-parts combination comprising at least one freeze-dried molded body and at least one aqueous solution containing at least one active ingredient and/or optionally at least one excipient, where the components are spatially arranged.
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