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NOUVEAUX ANALOGUES UTILISES EN TANT QUE MODULATEURS DU RECEPTEUR DES ANDROGENES ET DU RECEPTEUR DES GLUCOCORTICOIDES
专利权人:
ONCOSTELLAE; S.L.
发明人:
KURZ, GUIDO,CAMACHO GOMEZ, JUAN
申请号:
CA3079804
公开号:
CA3079804A1
申请日:
2018.11.06
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to novel dihydropyridine derivatives of formula (I): as modulators of nuclear receptors selected from androgen receptor and glucocorticoid receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to the use of said for manufacturing a medicament for the treatment of pathological conditions or diseases that can improve by modulation of androgen receptor and/or glucocorticoid receptor, selected from cancer, metastasizing cancers, benign prostate hyperplasia, polycystic ovary syndrome (PCOS), hair loss, hirsutism, acne, hypogonadism, muscle wasting diseases,cachexia, Cushing's syndrome, anti-psychotic drug induced weight gain, obesity, post-traumatic stress disorder and alcoholism.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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