YEON YOUNG EUN,연영은,KIM YOUNG JU,김영주,LEE JONG SEOK,이종석,HAN BEOM KU,한범구,KIM HYUN IL,김현일,PARK CHARL SE,박철세
申请号：
KR1020190150238
公开号：
KR1020190132331A
申请日:
2019.11.21
申请国别(地区):
KR
年份:
2019
代理人:
摘要：
The present invention relates to a novel bacteriophage PA4 having a killing ability specific to Pseudomonas aeruginosa, particularly carbapenem-based antibiotic resistant Pseudomonas aeruginosa, a pharmaceutical composition, an antibiotic composition, a feed additive composition, a feed, a disinfectant or a washing agent for preventing or treating infectious diseases caused by Pseudomonas aeruginosa, which include the bacteriophage, and a method for preventing or treating infectious diseases caused by Pseudomonas aeruginosa, which includes a step of administrating the bacteriophage to an object. The method for preventing or treating infectious diseases caused by Pseudomonas aeruginosa using the bacteriophage PA4 has very high specificity to Pseudomonas aeruginosa, and particularly to carbapenem resistant Pseudomonas aeruginosa compared to a conventional chemical material such as antibiotics or the like, and the bacteriophage PA4 is infected to Pseudomonas aeruginosa, thereby having excellent bacteriolytic activity and being strong to physiochemical stimulation. In addition, the bacteriophage PA4 of the present invention is not infected to a host other than bacteria except a human, an animal, a plant, or the like, and thus it is possible to solve a problem of antibiotic resistant bacteria due to abuse of antibiotics, a problem of residual antibiotics in food, and a problem of a wide range of host ranges. Accordingly, the bacteriophage PA4 of the present invention can be variously used in the fields of prevention or treatment of infectious diseases caused by Pseudomonas aeruginosa, antibiotic compositions, feed additive compositions, feeds, disinfectants, or washing agents.본 발명은 녹농균(Pseudomonasaeruginosa), 특히 카르바페넴(carbapenem)계 항생제 내성 녹농균에 특이적인 사멸능을 갖는 신규 박테리오파지 PA4, 상기 박테리오파지를 포함하는 녹농균에 의한 감염성 질병의 예방 또는 치료용 약학적 조성물, 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 개체에 투여하는 단계를 포함하는 녹농균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 PA4를 이용한 녹농균에 의한 감염성 질병의 예방 또는 치료 방법
