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Glycotargeting therapeutics
专利权人:
Ecole Polytechnique Federale de Lausanne
发明人:
Hubbell, Jeffrey A.,Wilson, David Scott
申请号:
AU2016325073
公开号:
AU2016325073A1
申请日:
2016.09.16
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Several embodiments of the present disclosure relate to therapeutic compositions configured to target the liver of a subject and that are useful in the treatment or prevention of one or more of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent. In several embodiments, the compositions are configured to target the liver and deliver antigens to which tolerance is desired. In several embodiments, the compositions are configured for clearance of a circulating protein or peptide or antibody associated with one or more of the above-mentioned maladies. Methods and uses of the compositions for induction of immune tolerance are also disclosed herein.
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