LINK, JOHN O.,MOSSMAN, CRAIG J.,LIU, JIE,WOO, SOON HYUNG
申请号:
ES07853752
公开号:
ES2535603T3
申请日:
2007.10.03
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
A compound that is: N- (1-cyanocyclopropyl) -5,4,4-difluoro-5-phenyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) pentanamide; N- (1-cyanocyclopropyl) -4,4-difluoro-4-phenyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) butanamide; N- (1-cyanocyclopropyl) -4,4-difluoro-5-cyclopropyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) pentanamide; N- (1-cyanocyclopropyl) -4,4-difluoro-4-cyclopropyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) butanamide; N- (1-cyanocyclopropyl) -4,4-difluoro-4-cyclohexyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) butanamide; N- (1-cyanocyclopropyl) -5,5-difluoro-5-cyclopropyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) pentanamide; N- (1-cyanocyclopropyl) -5,5-difluoro-5-phenyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) pentanamide; N- (1-cyanocyclopropyl) -5,5-difluoro-6-phenyl-2 (S) - (2,2,2-trifluoro-1 (S) - (4-fluorophenyl) ethylamino) hexanamide; or one of its pharmaceutically acceptable salts.Un compuesto que es: N-(1-cianociclopropil)-5 4,4-difluoro-5-fenil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)pentanamida; N-(1-cianociclopropil)-4,4-difluoro-4-fenil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)butanamida; N-(1-cianociclopropil)-4,4-difluoro-5-ciclopropil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)pentanamida; N-(1-cianociclopropil)-4,4-difluoro-4-ciclopropil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)butanamida; N-(1-cianociclopropil)-4,4-difluoro-4-ciclohexil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)butanamida; N-(1-cianociclopropil)-5,5-difluoro-5-ciclopropil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)pentanamida; N-(1-cianociclopropil)-5,5-difluoro-5-fenil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)pentanamida; N-(1-cianociclopropil)-5,5-difluoro-6-fenil-2(S)-(2,2,2-trifluoro-1(S)-(4-fluorofenil)etilamino)hexanamida; o una de sus sales farmac