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PHOSPHATE ADSORBENT
专利权人:
ВИФОР (ИНТЕРНАЦИОНАЛЬ) АГ (CH)
发明人:
ВИТЦЕЛЬ Гизела (DE),ГЕЙССЕР Петер (CH),ФИЛИПП Эрик (CH)
申请号:
RU2011140017/15
公开号:
RU2011140017A
申请日:
2010.03.01
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A composition containing a mixture of salts of calcium, magnesium and iron for use as a pharmaceutical preparation for the adsorption of phosphate in the body and / or from biological fluids, for internal and / or external use. The composition according to claim 1 for the treatment of hyperphosphatemia, for the treatment of patients with chronic renal failure (CKD) and / or the treatment of patients on hemodialysis. The composition according to claim 1 or 2, wherein the calcium and magnesium salts are selected from the group consisting of carbonates, bicarbonates, basic carbonates, acetates, oxides, hydroxides and mixtures thereof. A composition according to claim 1 or 2, wherein the iron salt is selected from the group consisting of iron oxide, iron hydroxide, iron oxyhydroxide, iron complex compounds, and mixtures thereof. The composition of claim 1 or 2, wherein the iron salt is selected from an iron (III) salt, iron (III) hydroxide and / or iron (III) oxyhydroxide and / or iron (III) oxides and / or their stabilized forms. A composition according to claim 1 or 2, wherein the iron salts are stabilized with carbohydrates and / or humic acid, sucrose and / or starch. The composition according to claim 1 or 2, in which the molar ratio of calcium to magnesium is 1: 0.02-20 and the molar ratio of calcium to iron is 1: 0.02-20.8. The composition according to claim 7, in which the molar ratio of calcium to magnesium is 1: 0.20-0.78 or 1: 0.80-0.99, or 1: 1.03-2.00.9. The composition of claim 8, in which the molar ratio of calcium to iron is 1: 0.02-0.65 or 1: 0.67-0.68, or 1: 0.7-1.50.10. The composition according to any one of claims 1, 2 or 8, 9 for the introduction of a mixture of salts of calcium, magnesium and iron in the total amount calculated on metallcal: 80 mg-2400 mg, which corresponds to 2-60 mmolmagnesium: 49 mg-729 mg, which corresponds to 2-30 mm1. Композиция, содержащая смесь солей кальция, магния и железа для применения в качестве фармацевтического п
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