By accurately assess breathing, it is an object of the present invention to provide a particle beam therapy system and the breathing guidance system can guide the proper breathing. Real breath measurement unit which outputs (R rl (t)) the actual respiration signal breathing guidance control unit which generates (R tj (t)) the goal respiration signal of breathing for the induction and (7cC), was measured actual patients breathing as a unit and (7a), 1 cycle (R tj (t)) of the target respiration signal (T res), and data (R tj (t)) of the respiration signal goal, goal respiratory signal (R tj (t)) (a 1, b 1) coefficients of trigonometric functions which form a corresponding pair of the first order in the case of the Fourier series expansion for, and the data (R rl (t)) of the actual respiratory signal collected in synchronization with the data breathing that compares gain was calculated, which was obtained from (1, b 1 a) factor (G tj, G rl) and phase (φ tj, φ rl) and, to evaluate the deviation of the actual breathing with respect to the target respiration signal I provided the evaluation unit, and (7cE).呼吸を正確に評価することにより、呼吸を適切に誘導できる呼吸誘導装置および粒子線治療装置を得ることを目的としている。呼吸誘導用の目標呼吸信号(Rtj(t))を生成する呼吸誘導制御部(7cC)と、患者の実呼吸を測定した実呼吸信号(Rrl(t))を出力する実呼吸測定部(7a)と、目標呼吸信号(Rtj(t))の1周期(Tres)を単位として、目標呼吸信号(Rtj(t))のデータと、目標呼吸信号(Rtj(t))のデータと同期して収集した実呼吸信号(Rrl(t))のデータと、に対してフーリエ級数展開した場合の一次項に相当する対をなす三角関数の係数(a1,b1)を計算し、係数(a1,b1)から求めたゲイン(Gtj,Grl)と位相(φtj,φrl)とを比較して、目標呼吸信号に対する実呼吸のずれを評価する呼吸評価部(7cE)と、を備える。
