CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE D'AIX-MARSEILLE
发明人:
AZIZ MOQRICH,MARIE-CLAIRE DELFINI,ANNABELLE MANTILLERI
申请号：
US15841342
公开号：
US20180110829A1
申请日:
2017.12.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a method of using a TAFA4 protein or an agonist thereof for preventing, alleviating or treating pain in a subject. In one embodiment, the invention provides a method of treating pain in a subject by administering a TAFA4 protein or an agonist thereof to the subject. The TAFA4 can have the amino acid sequence of SEQ ID NO: 1 or 2 or a sequence having at least 90% sequence identity to SEQ ID NO: 1 or 2. The TAFA4 agonist can also be a peptide comprising 10 to 60 consecutive amino acid residues of SEQ ID NO: 1 or 2. Also described herein are pharmaceutical compositions, their preparation and uses as well as methods for preventing, alleviating or treating pain using such compounds and compositions.
