Michael Daly,Elena K Gaidamakova,Ian A. Myles,Patricia A. Valdez,Sandip K. Datta
申请号:
US14355063
公开号:
US20140314810A1
申请日:
2012.11.01
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention provides methods of producing vaccines directed against methicillin-resistant Staphylococcus aureus (MRSA) or Venezuelan equine encephalitis virus (VEEV), with the methods comprising culturing, harvesting and/or suspending the MRSA or VEEV in the presence of a radiation-protective composition and irradiating the MRSA with a dose of radiation sufficient to render the MRSA or VEEV replication-deficient and/or non-infective. The radiation-protective compositions used in the methods of the present invention comprise at least one nucleoside, at least one antioxidant and at least one small peptide.