Interferon alpha-2B modified by polyethylene glycol and methods of preparation thereof

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专利权人:

Tiebing Wang;Fenghong Yin;Lu Zhuang;Min Liu;Yong Zhang;Qingjiang Xiao;Tianle Xu;Li Sun;Shihong Luo;Weidong Zhou

发明人:

Weidong Zhou,Qingjiang Xiao,Li Sun,Tiebing Wang,Fenghong Yin,Shihong Luo,Lu Zhuang,Min Liu,Tianle Xu,Yong Zhang

申请号：

US12676525

公开号：

US08597635B2

申请日:

2007.09.04

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to interferon-α2b modified with Y-shaped branched polyethylene glycol (PEG) at a single Lys residue and the preparation thereof. The peglated IFN-α2b can be used for the preparation of a medicament for treating a disease, e.g. viral infections such as Hepatitis C.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/