MONOMETHYLVALINE COMPOUNDS CONJUGATED WITH ANTIBODIES
- 专利权人:
- 发明人:
- 申请号：
- HK13101170.5
- 公开号：
- HK1173682A
- 申请日:
- 2007.05.28
- 申请国别(地区):
- HK
- 年份:
- 2013
- 代理人:
- 摘要：
- Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.
- 来源网站：
- 中国工程科技知识中心
