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КОМПОЗИЦИИ ДЛЯ ПОДКОЖНОГО ВВЕДЕНИЯ ФИЗИОЛОГИЧЕСКИ АКТИВНЫХ СРЕДСТВ
专利权人:
НОВАРТИС АГ (CH)
发明人:
МЕЙЕР Штефан (CH),ЛАНГ Орели (CH)
申请号:
RU2013157834/15
公开号:
RU2013157834A
申请日:
2012.05.24
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A composition for subcutaneous administration of a physiologically active agent comprising (a) a copolymer of ethyl acrylate / methyl methacrylate, (b) ethanol, isopropanol or a mixture thereof, (c) water, and (d) at least one physiologically active sredstvo.2. Composition according to claim. 1, wherein (b) represents izopropanol.3. Composition according to claim. 1 or 2, wherein at least one physiologically active agent (d) is selected from the group consisting of an analgesic pharmaceutically active substances, antihistamines, antifungals and nikotina.4. Composition according to Claim. 1, wherein at least one physiologically active agent (d) is diclofenac or a pharmaceutically acceptable sol.5. Composition according to claim. 1, containing copolymers EA / MMA (a) calculated in pure form in an amount from 2% to 30% (wt.). 6. Composition according to Claim. 1, containing the component (b) [ethanol and / or isopropanol] in an amount of from 35% to 90% (wt.). 7. Composition according to claim. 1, containing water (c) in an amount of from 5% to 40% (wt.). 8. . Composition according to claim 1, containing copolymers EA / MMA (a) calculated in pure form, and component (b) in a weight ratio of from 1: 1 to 1: 45.9. Composition according to claim. 1, further comprising from 0.5 to 8% (wt.) of a compound selected from the group consisting of oleyl alcohol, oleic acid, linoleic alcohol, linolenic acid, myristyl alcohol, dimethyl sulfoxide, thymol, menthol, and any smesey.10. A composition according to claim. 3, comprising at least one physiologically active agent (d) non-steroidal anti-inflammatory drug, for use in treating boli.11. Composition according to claim. 3, comprising at least one physiologically active agent (d) non-steroidal proti1. Композиция для подкожного введения физиологически активного средства, содержащая(а) сополимер этилакрилата/метилметакрилата,(b) этанол, изопропанол или их смесь,(с) воду, и(d) по меньшей мере одно физиологически активное средство.2
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