The present invention relates to a vector construct, and more specifically to a vector construct comprising human hypoxia inducible factor α gene. The present invention also relates to a transgenic animal or cell containing said vector construct which in the presence of an inducing agent expresses human hypoxia inducible factor α gene causing hair growth suppression. The present invention further relates to use of this animal model for determining the efficacy of methods for suppressing or inducing hair growth and discover further molecules which regulate hair growth.
