Inhibitory proteasomu do leczenia zaburzenia związanego z nagromadzeniem nieuszkodzonego, nieprawidłowego białka lub raka农业专利-农业学术服务平台

专利权人:: Assistance Publique Hôpitaux de Marseille;Université d'Aix-Marseille;INSERM (Institut National de la Santé et de la Recherche Médicale);Association Francaise Contre Les Myopathies;CENTRE NATIONAL DE L

发明人:: LEVY, NICOLAS,CAU, PIERRE,DE SANDRE-GIOVANNOLI, ANNACHIARA,HARHOURI, KARIM,PERRIN, SOPHIE,NAVARRO, CLAIRE,CHARTIER, AYMERIC,SIMONELIG, MARTINE

摘要：: The invention relates to a proteasome inhibitor for use for treating and/or preventing a disorder related to an accumulation of a non-degraded abnormal protein, particularly a premature ageing disorder. The invention also relates to the use of proteasome inhibitors for attenuating physiological ageing. The invention also relates to the use of proteasome inhibitors in the treatment and/or prevention of age-related disorders and their metabolic consequences. The invention also relates to the dermato logical, dermo cosmetic or cosmetic use of a proteasome inhibitor for preventing and/or attenuating skin ageing. The invention also relates to the use of proteasome inhibitors in the treatment of cancer.