GYEONGBUK INSTITUTE FOR BIO INDUSTRY;ANDONG NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;KYUNGOKSAMBO CO., LTD. AGRICULTURAL CO.
发明人:
SOHN HO YONG,LEE MAN HYO,KANG SUK MOON
申请号：
KR20180031858
公开号：
KR20190110206A
申请日:
2018.03.20
申请国别(地区):
KR
年份:
2019
代理人:
摘要：
The present invention relates to a use of a restorative herb medicine prepared by adding Silk of Zea mays Linne and Cucurbita moschata. More specifically, the present invention relates to a pharmaceutical composition and health functional food for preventing or treating/ameliorating thrombosis through strong blood coagulation enzyme/factor inhibiting activity and platelet aggregation inhibiting activity by adding Silk of Zea mays Linne and Cucurbita moschata to an existing restorative herb medicine comprising Rehmannia glutinosa var. purpurea, Poria cocos, ginseng and honey as main ingredients. As being proved through an embodiment of the present specification, a restorative herb medicine having a Silk of Zea mays Linne and Cucurbita moschata as an active ingredient of a pharmaceutical composition and health functional food of the present invention: has excellent appealability by adding Silk of Zea mays Linne and Cucurbita moschata； exhibits strong antithrombotic activity by inhibiting thrombogenesis-related enzymes and blood coagulation factors； does not show hemolytic activity to human red blood cells at all； has excellent thermal stability； and does not exhibit loss in effects of inhibiting the thrombogenesis-related enzymes and the blood coagulation factors even at an acidic condition of pH 2 and within blood plasma at the same time such that the present invention is expected to be used for prevention and treatment of thrombosis such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation. In addition, the active ingredient is processed into various forms such as extract, powder, pill, tablet, and the like to be taken at any time. Accordingly, the present invention is extremely useful in pharmaceutical and food industries.본 발명은 옥미수(Silk ofLinne) 및 호박()을 가미하여 제조되는 경옥고의 용도에 관한 것으로서, 보다 상세하게는, 기존 생지황, 백복령, 인삼 및 벌꿀을 주성분으로 하는 경옥고에 옥미수와 호박을 가미하여 강력한 혈액 응고 효소/인자 저해 활성 및 혈소판 응집 저해 활성을 통한 혈전증의 예방 또는 치료/개선용 약학적 조성물 및 건강 기능 식품에 관한 것이다. 본 발명의 약학적
