ANDROGEN RECEPTOR MODULATING COMPOUNDS

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专利权人:

ORION CORPORATION

发明人:

WOHLFAHRT, GERD,TORMAKANGAS, OLLI,SALO, HARRI,HOGLUND, IISA,KARJALAINEN, ARJA,KNUUTTILA, PIA,HOLM, PATRIK,RASKU, SIRPA,VESALAINEN, ANNIINA

申请号：

NZ59874710

公开号：

NZ598747A

申请日:

2010.10.27

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

598747 Compounds of formula (I) wherein R1 to R16, A. B and E are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as tissue-selective androgen receptor modulators (SARM) and are particularly useful as medicaments in the treatment of prostate cancer and other AR dependent conditions and diseases where AR antagonism is desired.

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