МАННИНГ, Памела (US),ПЮРО, Робин (US),АЛМАГРО, Хуан, К. (US),КАРР, Коберт, У. (US)
申请号：
RU2018124859
公开号：
RU2018124859A
申请日:
2016.09.17
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
Provided are anti-CD47 monoclonal antibodies (anti-CD47 mAbs) with distinct functional profiles as described herein, methods to generate anti-CD47 mAbs, and to methods of using these anti-CD47 mAbs as therapeutics for the prevention and treatment of solid and hematological cancers, ischemia-reperfusion injury, cardiovascular diseases, autoimmune diseases, inflammatory diseases or as diagnostics for determining the level of CD47 in tissue samples.
