Offer of numerator probe for Pancreatic island imaging. The below-mentioned formula the numerator probe which includes the polypeptide or the aforementioned polypeptide and possesses homology the polypeptide which are displayed with the polypeptide which is displayed with (1). Z-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSX-NH2 (1) (array number 1)In the above-mentioned formula (1), as for X , shows the lysine residue which the indicator is done with the basis where the amino group of the side chain is displayed with below-mentioned formula (i).In formula (i), A shows the aromatic hydrocarbon group or the aromatic heterocycle basis, R, C, N, O, F, Cu, Ga, Ga, Br, Br, Br, Tc and In, shows the substituent which includes I, I, I or I, R hydrogen atom or R shows the substituent which differs, R, the join hand, shows either the C C alkylene basis and the C C oxyalkylene basis.膵島イメージング用分子プローブの提供。下記式(1)で表されるポリペプチドで表されるポリペプチド又は前記ポリペプチドと相同性を有するポリペプチドを含む分子プローブ。Z-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSX-NH2 (1) (配列番号1)上記式(1)において、「X」は、側鎖のアミノ基が下記式(I)で表される基によって標識されたリジン残基を示す。式(I)において、Aは、芳香族炭化水素基又は芳香族複素環基を示し、R1は、11C、13N、15O、18F、64Cu、67Ga、68Ga、75Br、76Br、77Br、99mTc、111In、123I、124I、125I又は131Iを含む置換基を示し、R2は、水素原子又はR1とは異なる置換基を示し、R3は、結合手、C1-C6アルキレン基及びC1-C6オキシアルキレン基のいずれかを示す。
