PROBLEM TO BE SOLVED: To provide: a semaphorin inhibitory agent an in-the-peripheral or central neuron-regeneration accelerating agent containing as an active ingredient the semaphorin inhibitory agent and a prophylactic or therapeutic agent and the like for neurological diseases associated with neuronal degeneration such as spinal cord injury, containing the neuron-regeneration accelerating agent.SOLUTION: There is provided a compound or pharmaceutically acceptable salt thereof represented by the formula (1). [In which, R1 and R2 each independently represent a hydrogen atom or a carboxyl group, R3 and R4 each independently represent a hydrogen atom or a hydroxyl group, and X represents a single bond.]SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】セマフォリン阻害剤、かかるセマフォリン阻害剤を有効成分として含有する、末梢または中枢における神経再生促進剤、かかる神経再生促進剤を含有する脊髄損傷等の神経変性を伴う神経性疾患の予防剤もしくは治療剤等を提供する。【解決手段】式(1):【化1】[式中、R1およびR2はそれぞれ独立して、水素原子またはカルボキシル基を表し、R3およびR4はそれぞれ独立して、水素原子または水酸基を表し、Xは、単結合を表す。]で表される化合物またはその薬学上許容される塩。【選択図】なし
