Giuseppe ASTARITA,Mark S. DENNIS,Jennifer A. GETZ,Anastasia HENRY,Mihalis KARIOLIS,Cathal MAHON,Adam P. SILVERMAN,Ankita SRIVASTAVA,Julie ULLMAN,Junhua WANG,Joy Yu ZUCHERO
申请号:
US16649943
公开号:
US20200277584A1
申请日:
2018.10.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are fusion proteins that comprise an enzyme replacement therapy enzyme and an Fc region, as well as methods of using such proteins to treat a lysosomal storage disorder. Methods for transporting agents across the blood-brain barrier are also provided herein.