PROBLEM TO BE SOLVED: To provide a pemetrexed containing liquid pharmaceutical composition having excellent long-term storage stability.SOLUTION: A liquid pharmaceutical composition comprises (A) pemetrexed, its pharmaceutically acceptable salt, or their solvates, (B) cysteine, its pharmaceutically acceptable salt, or their solvates [preferably, a component comprising L-cysteine, its pharmaceutically acceptable salt, or their solvates], and (C) a chelating agent [preferably, a component comprising sodium edetate or its hydrate].SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】長期保存安定性に優れるペメトレキセド含有液体医薬組成物を提供すること。【解決手段】(A)ペメトレキセド、その薬学的に許容できる塩、又はそれらの溶媒和物、(B)システイン、その薬学的に許容できる塩、又はそれらの溶媒和物〔好ましくは、L-システイン、その薬学的に許容できる塩、又はそれらの溶媒和物を含む成分〕、及び(C)キレート化剤〔好ましくは、エデト酸ナトリウム又はその水和物を含む成分〕を含有してなる液体医薬組成物。【選択図】なし
