Alaric J. Dyckman,Dharmpal S. Dodd,Tasir Shamsul Haque,Louis J. Lombardo,John E. Macor,Christopher P. Mussari,Laxman Pasunoori,Michael A. Poss,Sreekantha Ratna Kumar,Shoshana L. Posy,David R. Tortolan
申请号:
US16330964
公开号:
US10660877B2
申请日:
2017.09.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are compounds of Formula (I) N-oxide, or salt thereof, wherein R1, R2, R3, R4, R5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.