A polypeptide having a heavy chain variable region and/or light chain variable region that specifically binds to Ror2 protein as well as antibodies and antibody fragments containing the heavy chain variable region and/or the light chain variable region that bind to Ror2 protein. Pharmaceutical compositions and kits comprising the polypeptide or antibodies and antibody fragments containing the polypeptide are also provided.本發明係關於一種特異性結合於Ror2蛋白質之具有重鏈可變區及/或輕鏈可變區之多肽,以及結合於Ror2蛋白質之含有該重鏈可變區及/或該輕鏈可變區之抗體及抗體片段。亦提供包含該多肽或含有該多肽之抗體及抗體片段的醫藥組合物及套組。