Yi-Ju KO,Jheng-Sian LI,Maggie LU,On LEE,Ping-Fu CHENG,Chun-Min LIU
申请号：
US15341834
公开号：
US20170119902A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
An antibody-drug conjugate (ADC) of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), p is an integer ranging from 1 to 26, A is an antibody, and -(L-D) is a linker-drug unit. L is a linker unit having a glycopeptide, and D is a drug unit. The antibody is conjugated to the linker unit through a cysteine residue of the antibody. A method for forming an antibody-drug conjugate (ADC) is also provided.A-(L-D)p (I)
