RNA INTERFERENCE AGENTS FOR GST-PI GENE MODULATION

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专利权人:

发明人:

YING WENBIN

申请号：

IN201717026030

公开号：

IN201717026030A

申请日:

2017.07.21

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

This invention provides compounds, compositions and methods for modulating the expression of human GST-pi using RNA interference. The RNA interference molecules can be used in methods for preventing or treating diseases such as malignant tumor. Provided are a range of siRNA structures, having one or more of nucleotides being modified or chemically-modified. Advantageous structures include siRNAs with 2-deoxy nucleotides located in the seed region, as well as other nucleotide modifications

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/