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SOLVENT-FREE METHOD OF ENCAPSULATING A HYDROPHOBIC ACTIVE
专利权人:
Agency for Science; Technology and Research
发明人:
Praveen Thoniyot,Parijat Kanaujia,Alexander M. Van Herk
申请号:
US16498284
公开号:
US20200179248A1
申请日:
2018.03.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Present disclosure relates to a solvent-free method of encapsulating a hydrophobic active in personal care, hydrophobic active in crop protection or a hydrophobic active pharmaceutical ingredient (API) in polymeric nanoparticles. The method includes mixing the hydrophobic active in a polymer melt, wherein the polymer melt comprises a melt of a block co-polymer, wherein the polymer melt acts as a solvent for the hydrophobic active. The method further includes maintaining the polymer melt in water for sufficient time to allow self-assembly of the block co-polymer to encapsulate the hydrophobic active therein.
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