An apparatus and method for cognitive assessment and training of an animal subject. A subject is placed in a testing environment, such as a subject chamber of a cognitive assessment and training apparatus. At least one cognitive assessment and training session comprising a plurality of trials is performed. In a trial, a trial assembly is prepared at a first level. The trial assembly includes at least one stimuli and a reward, where a target stimuli of the at least one stimuli is associated with the reward. The subject is allowed access to the stimuli. When a correct response is determined from the subject, the subject is allowed to access a reward associated with the correct response. The subject is advanced to trials at a next level when a learning criterion is reached. At least one cognitive assessment score is generated based on the plurality of trials and the at least one cognitive assessment and training session.