A catheter device (1000) for treating a disease or disorder of a paranasal sinus having an ostium which opens into said paranasal sinus, said device comprising: a catheter shaft (1002) having a distal end, said catheter shaft being suitable for advancing, distal end first, through the ostium and into the paranasal sinus； a distal balloon (1006) for positioning inside the paranasal sinus adjacent to the ostium； a proximal balloon (1004) for positioning outside the paranasal sinus adjacent to the ostium； and at least one balloon inflation lumen extending through the catheter shaft (1002) for inflation of said distal and proximal balloons (1006,1004), said device further comprising a lumen that is sized to receive a guidewire such that the device may be advanced over a guidewire.
