An improved catheter attachment apparatus is provided for use in reducing infections associated with a percutaneous medical device, such as a catheter. Such a barrier system can include: a barrier device having a catheter-receiving surface or enclosed tube and an adhesive composition configured for adhering to skin. The improved catheter attachment apparatus forms a physical barrier against microbes at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin, yet permits ready access by medical personnel for readjusting the catheter and/or any sutures used therewith.