Described herein are example methods and systems for neuro-behavioral relationships in dimensional geometric embedding (N-BRIDGE), which includes a comprehensive, data-driven analytic framework for mapping the multi-dimensional relationships between neural and behavioral features in humans. N-BRIDGE allows mapping of variations along newly-defined data-driven behavioral dimensions that capture the geometry of behavioral/symptom variation to variation in specific neural features. A method for treating a patient based on neuro-behavioral mapping includes receiving, from a user interface of a computing device, behavioral data of a patient corresponding to mental health or cognitive status of the patient, predicting, by at least one processor of the computing device, a neural feature map for the patient representative of neural data based on the behavioral data, determining, by the at least one processor, a therapeutic associated with the neural feature map, and treating the patient with the therapeutic associated with the neural feature map.