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BIOCOMPATIBLE MATRICES FOR THE TRANSFER OF BIOLOGICAL MOLECULES
专利权人:
UNIVERSITY OF LEEDS
发明人:
Georg Feichtinger
申请号:
US16319000
公开号:
US20190233793A1
申请日:
2017.07.20
申请国别(地区):
US
年份:
2019
代理人:
摘要:
There is provided a biocompatible material for delivering a biological molecule to target location, the material comprising: —;a hydrogel matrix material, —;a divalent cation-phosphate nanoparticle (in particular Calcium Phosphate), —;and a biological molecule (in particular a nucleic acid) complexed with the nanoparticle; wherein the nanoparticle is embedded within the hydrogel matrix material. The biocompatible material, particularly when in a 3D form, can be used in the treatment of various diseases. A preferred method of embedding the nanoparticles and biological molecules in the matrix is by electrophoretic transfer.
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