The present disclosure relates to preservative compositions for and methods of preserving household formulations, such as detergents, or preserving topical cosmetic or toiletry formulations against microbiological contamination or growth. Specifically, the disclosure relates to preservative compositions comprising an effective amount of a quaternary amine compound, an effective amount of an antifungal, and a solvent. Further, the disclosure relates to cosmetic or toiletry formulations comprising such preservative compositions. The disclosure further relates to method of making and using such preservative compositions and such cosmetic or toiletry formulations comprising the same.