Roger Tsien,Todd Aguilera,Emilia Olson,Tao Jiang,Quyen Nguyen
申请号：
US13384591
公开号：
US09682151B2
申请日:
2010.07.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed herein, in certain embodiments, is a selective transport molecule with increased in vivo circulation. In some embodiments, a selective transport molecule disclosed herein has the formula (A-X-B-C)-M, wherein C is a cargo moiety A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids X is a linker and M is a macromolecular carrier.
