The General Hospital Corporation d/b/a Massachusettes General Hospital;Dana-Farber Cancer Institute, Inc.
发明人:
Anne Fletcher,Shannon J. Turley,Biju Parekkadan
申请号：
US16538578
公开号：
US20200061118A1
申请日:
2019.08.12
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
