An intravascular nano-bubbling oxygenator includes a catheter having a tube and a separating wall dividing the tube into a first tube wall and a second tube wall and to form a first lumen and a second lumen. The first tube wall has a hydrophobic outer surface and a plurality of nano-sized first pores extending therealong. The first lumen has a closed end and a first opening end connecting to a source of gaseous oxygen. The second lumen has a second opening end and a third opening end, wherein the first lumen is capable of transporting gaseous oxygen, and the second lumen is capable of transporting liquid from the second opening end to the third opening end.