Irradiation device for insertion into a hole in the body of a human patient to provide photodynamic therapy, the hole being the female reproductive tract or rectum, the device comprising: a housing (1, 21, 31, 51, 61, 71) adapted to be fully inserted and secured in the hole, containing the housing (1, 21, 31, 51, 61, 71) an LED lamp system (5, 25, 35, 45, 54, 62, 72) and a source of power (41, 68, 78) to power the LED lamp system (5, 25, 35, 45, 54, 62, 72), and the housing (1, 21, 31, 51, 61, 71) comprising a surface of treatment (2, 22, 32, 63, 73), the LED system being designed, when the device is in operation, to emit light from the treatment surface (2, 22, 32, 63, 73)； wherein the treatment surface (2, 22, 32, 63, 73) is at least partially transparent to said light and where the device is independently operative while it is located in the hole； wherein the treatment surface has a size and / or shape adapted for complementary adjustment with a treatment area inside the hole such that, when the device is in operation, the treatment area is illuminated by said light, characterized by that the housing has a flexible outer portion that can adjust its shape to configure a secure fit with the hole walls and the LED system is designed to emit light at a light intensity in the range of 1-50 mW / cm2.Dispositivo de irradiación para su inserción en un orificio del cuerpo de un paciente humano para proporcionar terapia fotodinámica, siendo el orificio el tracto reproductivo femenino o el recto, comprendiendo el dispositivo: un alojamiento (1, 21, 31, 51, 61, 71) adaptado para insertarse completamente y asegurarse en el orificio, conteniendo el alojamiento (1, 21, 31, 51, 61, 71) un sistema de lámpara LED (5, 25, 35, 45, 54, 62, 72) y una fuente de potencia (41, 68, 78) para alimentar el sistema de lámpara LED (5, 25, 35, 45, 54, 62, 72), y comprendiendo el alojamiento (1, 21, 31, 51, 61, 71) una superficie de tratamiento (2, 22, 32, 63, 73), estando concebido el sistema L
