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マンノース6-リン酸-ポリエチレングリコール結合体
专利权人:
公益財団法人東京都医学総合研究所
发明人:
桜庭 均,田島 陽一,川島 育夫,武岡 真司,岡村 陽介,久保田 恒平,望月 佑次,伊藤 学,水野 篤志,竹内 良人,西山 名津子
申请号:
JP2007029802
公开号:
JP5069920B2
申请日:
2007.02.08
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
Disclosed are: a compound which can impart a high accumulation property in the blood, high stability in the blood and excellent target cell tropism to a substance of interest a complex of the compound and a substance of interest and an aggregate comprising the complex. Specifically disclosed is a conjugate composed of mannose 6-phosphate bound to one terminus of a polyethylene glycol chain. Also specifically disclosed is a complex which is compose of a substance of interest modified with a conjugate composed of mannose 6-phosphate bound to one terminus of a polyethylene glycol chain. Further specifically disclosed is an aggregate composed of substances of interest associated or aggregated to each other, wherein the conjugate is bound to at least a part of the aggregate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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