Refers to the forms of ansolvatos free Crystalline base of 2 - hydroxy - 6 - ((2 - (1 - isopropyl - 1H pyrazole - 5 - il) pyridin-3-yl) methoxy) benzaldehyde (Compound 1) such as: (a) the way I whose x-ray diffraction Peaks 12.82\u00b0 Powder are selected, 15.74\u00b0, 16.03\u00b0, 16.63\u00b0, 17.60\u00b0, 25.14\u00b0 And, 25.82\u00b0 26.44\u00b0 (\u00b10.2) (b) \u00b02theta Form II whose Peaks of x-ray Powder diffraction are selected 13.37\u00b0, 14.37\u00b0, 19.95\u00b0 and 23.92\u00b0 (\u00b10.2 \u00b02theta) among others. Also refers to solvate the Free Base of Crystalline Compound 1. These forms are useful in the treatment of disorders mediated by Sickle hemoglobinSE REFIERE A FORMAS DE ANSOLVATOS DE LA BASE LIBRE CRISTALINA DE 2-HIDROXI-6-((2-(1-ISOPROPIL-1H-PIRAZOL-5-IL)PIRIDIN-3-IL)METOXI)BENZALDEHIDO (COMPUESTO 1) TALES COMO: A) LA FORMA I CUYOS PICOS DE DIFRACCION DE RAYOS X EN POLVO SE SELECCIONAN DE 12.82°, 15.74°, 16.03°, 16.63°, 17.60°, 25.14°, 25.82° Y 26.44° (±0.2 °2THETA) B) LA FORMA II CUYOS PICOS DE DIFRACCION DE RAYOS X EN POLVO SE SELECCIONAN DE 13.37°, 14.37°, 19.95° Y 23.92° (±0.2 °2THETA) ENTRE OTROS. TAMBIEN SE REFIERE A SOLVATOS DE LA BASE LIBRE CRISTALINA DEL COMPUESTO 1. DICHAS FORMAS SON UTILES EN EL TRATAMIENTO DE TRASTORNOS MEDIADOS POR LA HEMOGLOBINA DREPANOCITICA
