TAYLOR, DOUG,MCCLAIN, JIM,SMOKE, CLINT,COLE, MIKE,DEYOUNG, JAMES
申请号:
EP06787258
公开号:
EP1909973A4
申请日:
2006.07.14
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto the substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming the coating; and sintering the coating under conditions that do not substantially modify the morphology of the pharmaceutical agent.