Christopher L. Parks,Kevin J. Wright,Maoli Yuan,Christy K. Jurgens,Xinsheng Zhang,Arban Domi,Simon Hoffenberg,Maria J. Chiuchiolo,Svetlana Rabinovich,Aaron J. Wilson,Ivo C. Lorenz
申请号：
US13792103
公开号：
US09347065B2
申请日:
2013.03.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to methods of developing gene inserts that are more compatible with the host vectors by modifying a protein sequence to lessen potential interference with vector propagation while ensuring that the protein is expressed and processed efficiently and maintains desired structural features, and designing a gene with a nucleotide sequence that resembles the base composition of the host vector genome.
