LEE, JAE YONG,LEE, JONG SOO,KANG, BYUNG KYU,LEE, BYUONG WOO,LEE, SANG OH,YUN, DAE MYOUNG,BANG, JAE HUN,SOHN, KI YOUNG
申请号:
CA3088955
公开号:
CA3088955A1
申请日:
2019.01.11
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Disclosed is a method for producing calcobutrol used as an MRI contrast agent. The method for producing calcobutrol comprises the steps of: obtaining butrol represented by chemical formula 2 in the specification by reacting gadobutrol represented by chemical formula 1 in the specification with a decomplexing agent; and obtaining calcobutrol represented by chemical formula 3 in the specification by reacting the butrol with calcium ions.