The invention relates to a method for determining at least one applicable path (32) for the movement of an object, especially of a surgical and/or diagnostical device, in human tissue (14) or animal tissue by means of a data set of intensity data obtained by a 3D imaging technique, the applicable path (32) of movement connecting a starting position (28) of the device with a defined target location (30). According to the invention the method comprises the steps: defining the target location (30) of a reference point of the device and choosing at least one possible starting position of the reference point of the device； determining a candidate path of movement (18, 20, 22) between the corresponding possible starting position (24,26, 28) and the defined target location (30)； and evaluating the candidate path of movement (18, 20, 22) as being an applicable path (32) depending on information about local intensity extrema and/or intensity variation resulting from the intensity data along the candidate path of movement (18, 20, 22). The invention further relates to a corresponding computer-readable medium, a corresponding computer program product, and a corresponding computerized system.
