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透析の必要性を予測するためのBNP型ペプチド類の使用
专利权人:
エフ.ホフマン-ラ ロシュ アーゲー
发明人:
アマン-ザラン,イルディコ,モエクス,ヨアヒム,ブルガー,ハンス ウルリッヒ,エスクリグ,セザール,シェルハグ,アルミン,ドウアティ,フランク,ヘルマン,ズザナ
申请号:
JP2008054640
公开号:
JP5032372B2
申请日:
2008.03.05
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
The present invention relates to diagnosing the risk of developing a need for dialysis and/or predicting a need for dialysis, particularly in patients suffering from renal disorders. More particularly, the present invention relates to diagnosing the risk of developing a need for dialysis in a patient, comprising the steps of (a) measuring the level of a BNP-typc peptide or a variant thereof in a sample from the patient, (b) diagnosing the risk by comparing the measured level of the BNP-type peptide or a variant thereof to at least one reference level. The BNP-type peptide may for example be brain natriuretic peptide (BNP) or the N-terminal fragment of BNP, NT-proBNP. A need for dialysis can be present in patients suffering from any kind of renal disorder, e.g. in patients suffering from diabetes or chronic kidney disease. A need for dialysis may also include a need for any other kind of renal replacement therapy, including kidney transplantation or renal tissue transplantation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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