Michael DUNN,Jia SU,Jason MASTAITIS,Jesper GROMADA,Lori MORTON
申请号:
US16657000
公开号:
US20200123263A1
申请日:
2019.10.18
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides monoclonal antibodies that bind to the natriuretic peptide receptor 1 (NPR1) protein, and methods of use thereof. In various embodiments of the invention, the antibodies are fully human antibodies that bind to NPR1. In some embodiments, the antibodies of the invention are useful for activating NPR1 activity, thus providing a means of treating or preventing a disease, disorder or condition associated with NPR1 in humans.