The present invention relates to a HIFU device having a cartridge storage holder and a sterilization function, and more specifically, as a HIFU device having a cartridge storage holder and a sterilization function, a plurality of A moving means having a wheel, a display means installed on the upper part of the body body and displaying operation and operation status information for treatment and beauty of the HIFU device, and a probe holder installed on one side of the body body. A cart body provided; A cartridge holder disposed on a front surface of the body body provided in the cart body to accommodate and store a plurality of cartridges; A sterilization processing unit disposed at an upper end of the cartridge holder to sterilize a plurality of cartridges received and stored in the cartridge holder; A HIFU probe mounted on a probe cradle provided on one side of the body body of the cart body and generating high-intensity focused ultrasound for body skin treatment; A power supply unit for receiving the external power and supplying driving power of the display means, the sterilization processing unit, and the HIFU probe; And a control unit for controlling operation and display of the display means, control of a driving state of the sterilization processing unit, and a control operation state of the HIFU probe. According to the HIFU device having a cartridge storage holder and a sterilization function proposed in the present invention, a cartridge holder storing and storing a plurality of cartridges in a cart body of a skin care device, and a cartridge stored and managed in the cartridge holder are sterilized and sterilized. By further including a sterilization treatment unit for the HIFU probe, as well as the use of unique functions of skin treatment and beauty through the generation of high-intensity focused ultrasound using the HIFU probe, concerns of contamination and infection of cartridges used for procedures of various people can be prevented. I can do it. In