(57)< Abstract > Production manner of the granulation constituent which is suited for the production of the oral solid preparation which possesses the property which decays quickly with cheek intracavity, and the granulation constituent which is obtained. The tablet which is produced by this invention can decay inside the opening of the patient extremely among brief. That kind of system the senior citizen who possesses difficulty in swallowing the former medicine solid formulation and/or especially is useful in order to formulation to convert the medicine for the child.頬腔内で迅速に崩壊する特性を有する経口固形剤の製造に適した顆粒組成物の製造方法、並びに得られる顆粒組成物。本発明によって製造される錠剤は患者の口内でごく短時間のうちに崩壊し得る。そのようなシステムは、従来の医薬固形製剤を嚥下することに困難さを有する高齢者及び/又は小児用の薬剤を製剤化するために特に有用である。
