#$%^&*AU2017203461A120170608.pdf#####ITizp In N i 4182267_Ldex-23/05/2017 ABSTRACT Embodiments are directed to compositions and methods of treating migraine and related neurological disorders. In certain aspects, methods and compositions are for reducing cortical spreading depression and/or suppressing the neurochemical basis for chronic and acute migraine events, and provide methods and pharmaceutical compositions related to both acute and preventive therapies for migraine events and related headaches.
